carcinogens in tobacco

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  • Harmful Chemicals in Tobacco Products American Cancer Society

    Tobacco smoke is made up of thousands of chemicals, including at least 70 known to cause cancer. These cancer-causing chemicals are referred to as carcinogens. Some of the chemicals found in tobacco smoke include: Nicotine (the addictive drug that produces the effects in the brain that people are looking for) Hydrogen cyanide Formaldehyde Lead Arsenic
    https://www.cancer.org/cancer/cancer-causes/tobacco-and-ca...

  • Cancer - How Tobacco Smoke Causes Disease: The Biology and

    An overview of the metabolism of six carcinogens in tobacco smoke that are implicated in the formation of DNA adducts identified in human tissues is presented in Figure 5.3. The six carcinogens are BP, NNK, N-nitrosodimethylamine , NNN, ethylene oxide, and 4-ABP.
    https://www.ncbi.nlm.nih.gov/books/NBK53010

  • Carcinogenic effect of tobacco smoke

    Polycyclic aromatic hydrocarbons (PAHs) and volatile N-nitrosamines, and also tobacco specific N-nitrosamines are considered to be the major carcinogens in tobacco smoke. To exert carcinogenic effect these compounds require previous metabolic activation by biotransformation enzymes. Individual susceptibility to chemical carcinogens is genotype and phenotype dependent.
    https://pubmed.ncbi.nlm.nih.gov/20361554

  • Carcinogens in Tobacco Smoke - Canada.ca

    Table 2: Examples of carcinogens in tobacco smoke with their IARC classification IARC
    https://www.canada.ca/en/health-canada/services/publicatio...

  • Tobacco smoke carcinogens and breast cancer

    Tobacco smoke carcinogens and breast cancer. Cigarette smoking is an established cause of a variety of cancer types, but its role in breast cancer etiology is not clear. In this report, the potential role of cigarette smoke carcinogens as causes of human breast cancer is evaluated. Of over 60 known carcinogens in tobacco smoke, several are kno . Cigarette smoking is an established cause of a variety of cancer types, but its role in breast cancer etiology is not clear.
    https://pubmed.ncbi.nlm.nih.gov/11921179


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  • Tobacco-related carcinogenesis in head and neck cancer

    Tobacco Carcinogens. Since the Surgeon Generals report in 1964, there has been tremendous effort to study the carcinogenic effects of tobacco products. These research efforts have led to significant advances in understanding the constituents of tobacco products.
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709040

  • How Do Cigarettes Cause Cancer? Memorial Sloan Kettering

    Among the 7,000 or so different chemicals in cigarette smoke, more than 70 are known to be carcinogens. The most well-studied of these is benzo apyrene (BP). BP is one of several ring-shaped chemicals called polycyclic aromatic hydrocarbons that are produced when organic matter, such as a tobacco leaf, is burned.
    https://www.mskcc.org/news/how-do-cigarettes-cause-cancer

  • O4 fall newsletter

    Having smoked cigarettes at some time in their lives. Though smoking prevalence has decreased in women by 25 percent from its peak in the 1960s, nearly one-quarter of women still smoke. Lung Cancer and Women There is still some debate as to whether or not women are more susceptible to tobacco carcinogens than men.
    https://idph.illinois.gov/about/womenshealth/newsletters/f...


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